Biochemistry

AMPK

AMP-activated protein kinase — the master cellular energy sensor; target of MOTS-c.

Definition

AMPK is activated when cellular ATP drops, shifting metabolism toward energy production, glucose uptake, and mitochondrial biogenesis. MOTS-c and other peptides activate AMPK to improve metabolic flexibility.

Related terms

Compounds that reference AMPK

Back to the full peptide glossary.