Moderate EvidenceResearch Only

Melanotan II: What the Research Shows

Also known as: MT-2, MT-II

A melanocortin receptor agonist that stimulates melanin production (tanning) and has sexual function effects. Significant safety concerns.

This content is for educational purposes only and is not medical advice. Consult a qualified healthcare provider before making any health decisions. Full disclaimer

Quick Facts

Category✨ Skin & Hair
Amino Acids7
Molecular Weight1024.18 Da
FormulaC50H69N15O9
FDA StatusResearch Only
Evidence RatingModerate
Human TrialsYes (6)
WADA StatusNot prohibited
Routessubcutaneous
Last Reviewed2026-03-11

Regulatory Status

Not FDA-approved. Sold illegally as a tanning product. FDA has issued multiple warnings about unlicensed products.

Researched Applications

Skin tanningErectile dysfunction (research)Sun protection (research)

Key Research (1 studies cited)

Melanocortin-based therapeutics for erection and libido dysfunction

review

Hadley ME, et al. (2006) — International Journal of Impotence Research

Review of melanotan II showing both tanning and sexual function effects via melanocortin receptor activation.

Key finding: Melanotan II demonstrated both skin tanning and pro-erectile effects in human studies, leading to development of PT-141.

PubMed: 16107869

About this article: Written by the PeptideMark Research Team. Last reviewed 2026-03-11. All factual claims are cited to peer-reviewed sources. PubMed links open in a new tab for independent verification. Editorial methodology · Medical disclaimer

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Last reviewed: 2026-03-11