Peptide Guides
In-depth, evidence-based educational resources. Every claim is cited, every statement rated by the strength of supporting research.
Featured Guides
What Are Peptides? A Science-Based Introduction
Understand the basics of peptide biology — what they are, how they work in the body, and why researchers study them.
Peptides for Weight Loss: What the Research Shows
A comprehensive comparison of peptides studied for weight management — from FDA-approved GLP-1 drugs to research compounds.
All Guides
FDA Regulation of Peptides: What You Need to Know
Navigate the complex regulatory landscape of peptides, from approved medications to research chemicals.
Understanding Our Evidence Ratings
How PeptideMark evaluates and rates the scientific evidence behind each peptide compound.
Growth Hormone Secretagogues Explained
An overview of GHS peptides — CJC-1295, Ipamorelin, Sermorelin, and more — with research context.
GLP-1 Receptor Agonists: From Semaglutide to Retatrutide
The science behind GLP-1 RAs, their mechanisms of action, clinical trial results, and current regulatory status.
How to Reconstitute Peptides: Step-by-Step
A detailed walkthrough of reconstituting lyophilized peptides with bacteriostatic water, including dosage calculations.
Peptide Storage & Handling Best Practices
How to properly store, handle, and maintain peptide integrity — temperature, light exposure, and shelf life considerations.
How to Read Peptide Research Papers
A guide to evaluating peptide studies — understanding study design, sample sizes, statistical significance, and common pitfalls.