Longevity & Anti-Aging Peptides: Research Evidence Guide
Longevity-focused peptides like Epithalon (Epitalon), MOTS-c, and NAD+ precursors are studied in the context of aging biology and cellular health. Evidence in this category is generally preliminary, with most research limited to animal models and cell culture studies. Epithalon research focuses on telomerase activation, while MOTS-c is a mitochondrial-derived peptide studied for metabolic regulation.
8 compounds in this category
CJC-1295CJC-1295 DAC, CJC-1295 without DAC
A growth hormone-releasing hormone (GHRH) analog studied for its ability to increase growth hormone and IGF-1 levels.
IpamorelinNNC 26-0161
A selective growth hormone secretagogue that stimulates GH release without significantly affecting cortisol or prolactin.
GHK-CuCopper Peptide, Glycyl-L-histidyl-L-lysine:copper(II)
A naturally occurring copper-binding tripeptide with research supporting skin remodeling, wound healing, and anti-aging properties.
SermorelinGeref, GHRH(1-29)NH2
A growth hormone-releasing hormone analog with a long history of clinical use for GH deficiency diagnosis and therapy.
EpithalonEpitalon, Epithalone
A tetrapeptide studied for its potential to activate telomerase and extend cellular lifespan, primarily in Russian research.
MOTS-cMitochondrial Open Reading Frame of the 12S rRNA-c
A mitochondria-derived peptide that targets the AMPK pathway, studied for metabolic regulation and exercise mimicry.
MK-677Ibutamoren, Nutrobal
An oral ghrelin mimetic (not a peptide) that stimulates growth hormone release. Has extensive human data but has not achieved FDA approval.
NAD+Nicotinamide Adenine Dinucleotide, NAD
A coenzyme critical for cellular energy and DNA repair. Not technically a peptide, but commonly discussed alongside peptide therapies in the longevity space.