Biochemistry

D-Amino Acid

A mirror-image amino acid that resists enzymatic degradation.

Definition

Most biological amino acids are the L-enantiomer. Incorporating D-amino acids into synthetic peptides slows proteolytic breakdown, extending half-life. CJC-1295 uses D-alanine to resist DPP-4 cleavage.

Related terms

Back to the full peptide glossary.