Biochemistry

GLP-2

Glucagon-like peptide-2 — an intestinal growth factor, parent molecule of teduglutide.

Definition

GLP-2 is co-secreted with GLP-1 from intestinal L-cells. Unlike GLP-1, its primary action is on intestinal mucosal growth. Teduglutide (a GLP-2 analog) is FDA-approved for short bowel syndrome.

Related terms

Back to the full peptide glossary.