PeptideMark

Safety Profile

CJC-1295 Side Effects: Frequency & Severity

CJC-1295 is generally well-tolerated; most side effects are related to transient GH elevation.

Educational content only. This page is compiled from published research for reference and is not medical advice, diagnosis, or treatment. Readers should verify claims against primary sources and consult a qualified healthcare provider before making any health decisions. Full disclaimer.

Common side effects

2

  • Injection site reactions

    Redness, itching, mild swelling.

  • Facial flushing

    Particularly in first weeks; typically transient.

Uncommon side effects

4

  • Headache

    Usually mild and transient.

  • Water retention

    Mild edema possible due to GH/IGF-1 elevation.

  • Increased appetite

    Related to GH effects.

  • Numbness/tingling in hands

    Carpal-tunnel-like symptoms from fluid retention.

Rare side effects

2

  • Hypoglycemia

    Possible with sustained GH elevation.

  • Insulin resistance

    Chronic supraphysiologic GH may impair glucose tolerance.

Contraindications

  • Active malignancy
  • Pregnancy and breastfeeding
  • Known hypersensitivity
  • Uncontrolled diabetes

Drug interactions

  • Corticosteroids — may blunt GH-releasing effect
  • Insulin — may require dose adjustment due to GH counter-regulatory effects

Special populations

Not FDA approved for any indication. Not recommended in pregnancy, pediatrics, or patients with active malignancy.

Overall safety summary

CJC-1295 is generally well-tolerated in pilot human studies. Side effects are usually related to GH elevation (water retention, carpal tunnel symptoms). Long-term safety data is limited.

CJC-1295 side effects: FAQ

Can CJC-1295 cause gynecomastia?

Gynecomastia is not a commonly reported effect, but theoretical risk exists if GH elevation promotes aromatization in susceptible individuals.

Back to CJC-1295 profileLegal statusResearch timeline