Human RCTPubMed ID: 17909207·2007

Tesamorelin, a Growth Hormone–Releasing Factor Analogue, Reduces Visceral Fat in HIV-Infected Patients

Falutz J, et al.

Annals of Internal Medicine, 2007 · n = 412

Key finding

Tesamorelin reduced visceral adipose tissue by 15.4% compared to placebo, without worsening glucose tolerance.

Summary

Pivotal RCT showing tesamorelin reduced visceral adipose tissue by 15.4% in HIV patients with lipodystrophy.

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Related compound

TesamorelinL5

An FDA-approved GHRH analog used for HIV-associated lipodystrophy, with research into broader metabolic and cognitive applications.

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