ReviewPubMed ID: 18525273·2008

Tesamorelin Safety and Tolerability in HIV-Positive Patients: Meta-Analysis of Phase 2 and Phase 3 Trials

Grunfeld C, Kotler DP, Dobs AS, et al.

AIDS, 2008

Key finding

Most common AEs: injection site reactions (34%), arthralgias (23%), fluid retention (18%); no carpal tunnel syndrome excess versus placebo.

Summary

Comprehensive safety review combining data from 600+ HIV-positive patients across multiple tesamorelin trials.

Read the study

The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.

View on PubMed

Related compound

TesamorelinL5

An FDA-approved GHRH analog used for HIV-associated lipodystrophy, with research into broader metabolic and cognitive applications.

More research on Tesamorelin

Tesamorelin Reduces Visceral Adiposity Independently of Changes in Appetite or Food Intake

Journal of Acquired Immune Deficiency Syndromes · 2016 · Human RCT

Tesamorelin Effects on Hepatic Steatosis in HIV-Positive Patients: Ultrasound and Transient Elastography Study

Journal of Hepatology · 2015 · Human RCT

Tesamorelin Effects on Serum Lipids and Apolipoprotein Profile in HIV Lipodystrophy

Journal of Lipid Research · 2014 · Human RCT

Tesamorelin Reduces Cardiovascular Risk Markers in HIV-Associated Lipodystrophy

The Journal of Clinical Endocrinology & Metabolism · 2013 · Human RCT

Hepatic and Renal Function During Tesamorelin Treatment in HIV-Positive Patients

Journal of Acquired Immune Deficiency Syndromes · 2013 · Human RCT