Human RCTPubMed ID: 20660054·2010

Tesamorelin Increases Serum IGF-1 and Improves Insulin Sensitivity in HIV Lipodystrophy

Andersen O, Friis-Møller N, Krarup T, et al.

The Journal of Clinical Endocrinology & Metabolism, 2010 · n = 87

Key finding

Tesamorelin increased serum IGF-1 by 156% (mean increase 78 ng/mL) and improved HOMA-IR by 23%.

Summary

Metabolic study examining tesamorelin effects on growth hormone signaling, IGF-1 levels, and insulin sensitivity in HIV patients.

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Related compound

TesamorelinL5

An FDA-approved GHRH analog used for HIV-associated lipodystrophy, with research into broader metabolic and cognitive applications.

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