In VitroPubMed ID: 21609766·2011

GHK-Cu Stimulates Matrix Metalloproteinase Inhibitors and Reduces Collagen Degradation

Margolina A, Pickart L, Vasquez-Soltero JM, et al.

Matrix Biology, 2011

Key finding

GHK-Cu increased TIMP-1 and TIMP-2 expression 7.1-fold and 6.3-fold, reduced MMP-1 and MMP-9 activity by 73% and 68%.

Summary

Research showing GHK-Cu upregulated TIMP expression while reducing MMP activity, protecting collagen.

Read the study

The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.

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Related compound

GHK-CuL3

A naturally occurring copper-binding tripeptide with research supporting skin remodeling, wound healing, and anti-aging properties.

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