ReviewPubMed ID: 24757392·2014

Melanocortin Peptides and Sexual Behavior: Preclinical Research and Clinical Implications

Wessells H, Fuciarelli K, Hannan JL, et al.

Current Sexual Health Reports, 2014

Key finding

MC4R agonists represent novel class of centrally-acting sexual enhancers; PT-141 selectivity reduces melanin effects versus melanotan II.

Summary

Comprehensive review of melanocortin-mediated sexual function, comparing melanotan II, PT-141, and other MC4R agonists with emphasis on mechanism and safety.

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