Melanocortin-4 Receptor Activation in the Hypothalamic Medial Preoptic Area Mediates Sexual Behavior in Rats
Kow LM, Weesner GD, Burnett AL, Pfaff DW.
Hormones and Behavior, 2015
Key finding
Selective MC4R agonism in hypothalamus increased male sexual behavior by 210% compared to control; blocked by MC4R antagonist.
Summary
Mechanistic study in rats demonstrating MC4R activation in medial preoptic area drives sexual motivation and erectile function through dopaminergic pathways.
Read the study
The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.
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