Oxytocin Pathway Modulation by Melanocortin-4 Receptor Activation in Paraventricular Nucleus
Kow LM, Dunning BE, Pfaff DW.
Behavioral Neuroscience, 2016
Key finding
MC4R agonist bremelanotide increased oxytocin neuron firing by 182% and sexual receptivity behavior by 145% in female rats.
Summary
Electrophysiologic study demonstrating MC4R-mediated modulation of oxytocin neurons in paraventricular nucleus and downstream sexual behavior effects.
Read the study
The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.
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