Human RCTPubMed ID: 29254941·2018

SUSTAIN-8: Semaglutide versus Sitagliptin in Type 2 Diabetes

Frias JP, Ahrens R, Bonora E, et al.

Diabetes Care, 2018 · n = 716

Key finding

Semaglutide 1.0mg achieved superior HbA1c reduction (-1.5% vs -0.7%, p<0.001), reduced cardiovascular death/MI/stroke by 27% versus sitagliptin.

Summary

Head-to-head trial demonstrating semaglutide superior to sitagliptin for glycemic control and cardiovascular parameters.

Read the study

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Related compound

SemaglutideL5

An FDA-approved GLP-1 receptor agonist used for type 2 diabetes and chronic weight management.

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