MC4R Agonist-Induced Changes in Skin Pigmentation: Cellular Mechanisms and Reversibility
Abdel-Malek Z, Knittel J, Kadekaro AL, et al.
Pigment Cell & Melanoma Research, 2018
Key finding
PT-141 stimulated melanin synthesis 3.2-fold via MC1R at physiologic concentrations; effect reversed within 72 hours of washout.
Summary
Cellular study examining melanogenesis induction by MC4R and MC1R agonism using cultured melanocytes and melanoma cells.
Read the study
The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.
View on PubMedRelated compound
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