Human RCTPubMed ID: 32107931·2020

STEP 2: Semaglutide for Weight Management with Comorbidities

Wadden TA, Bailey TS, Billings LK, et al.

Obesity, 2020 · n = 1210

Key finding

Semaglutide 2.4mg achieved 10.2% mean weight loss versus 3.2% placebo (p<0.001); 57% achieved ≥10% weight loss versus 16% with placebo.

Summary

Phase 3b trial of semaglutide 2.4mg in adults with obesity and comorbidities including diabetes and cardiovascular disease.

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