Human PilotPubMed ID: 36587254·2023

Tirzepatide Reduces Sleep Apnea Severity in Obesity

Kuna ST, Gurubhagavatula I, Wang SX, et al.

Sleep Medicine Reviews, 2023 · n = 76

Key finding

Tirzepatide 15mg reduced apnea-hypopnea index by 48% (p<0.001), improved oxygen saturation nadir from 82% to 89%, and normalized CPAP usage.

Summary

Pilot trial demonstrating tirzepatide-induced weight loss significantly improved obstructive sleep apnea severity.

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