Animal StudyPubMed ID: 9725926·1998

Ipamorelin, a new growth-hormone-releasing peptide, induces growth hormone release in a specific and selective manner

Raun K, Hansen BS, Johansen NL, et al.

Journal of Endocrinology, 1998

Key finding

Ipamorelin demonstrated true GH selectivity: no cortisol/ACTH/prolactin elevation even at supramaximal doses, establishing it as the cleanest GHRP.

Summary

Foundational selectivity study in swine showing ipamorelin stimulated GH with efficacy equal to GHRP-6 but without elevating ACTH, cortisol, or prolactin — even at 200x effective dose.

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Related compound

IpamorelinL3

A selective growth hormone secretagogue that stimulates GH release without significantly affecting cortisol or prolactin.

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