Biochemistry
mTOR
Mechanistic target of rapamycin — a kinase central to growth, protein synthesis, and autophagy regulation.
Definition
mTOR integrates nutrient, growth factor, and energy signals. Chronic mTOR activation accelerates aging in model organisms; its inhibition is a major longevity target. Peptides that affect insulin and IGF-1 signaling indirectly modulate mTOR.
Related terms
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