Biochemistry

NAD+

Nicotinamide adenine dinucleotide — essential cofactor for sirtuins, PARPs, and redox metabolism.

Definition

NAD+ is a central coenzyme in metabolism. NAD+ levels decline with age; precursors like NR and NMN aim to restore the pool to support sirtuin-dependent longevity signaling.

Related terms

SirtuinA family of NAD+-dependent deacetylases involved in longevity and metabolic regulation.
MitochondriaCellular organelles producing ATP; increasingly recognized as a target for longevity peptides.

Compounds that reference NAD+

NAD+A coenzyme critical for cellular energy and DNA repair. Not technically a peptide, but commonly discussed alongside peptide therapies in the longevity space.

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