Biochemistry
Sirtuin
A family of NAD+-dependent deacetylases involved in longevity and metabolic regulation.
Definition
Sirtuins (SIRT1-SIRT7) deacetylate target proteins using NAD+ as a substrate. They regulate DNA repair, metabolism, and stress response — and are central to caloric-restriction and NAD+ longevity theories.
Related terms
Compounds that reference Sirtuin
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