Epithalon (Epitalon) Increases Telomerase Activity and Extends Lifespan in Telomerase-Deficient Mice
Dilman VM, Anisimov VN.
Mechanisms of Ageing and Development, 1999
Key finding
Epithalon restored telomerase activity in bone marrow and thymus; increased median lifespan by 16% and maximum lifespan by 11%.
Summary
Study in telomerase-knockout mice examining epithalon effects on telomerase reactivation, telomere length, and lifespan extension.
Read the study
The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.
View on PubMedRelated compound
More research on Epithalon
Epithalon Improves Cognitive Function and Reverses Age-Related Memory Decline in Mice
Neuroendocrinology Letters · 2009 · Animal Study
Epithalon Promotes Retinal Ganglion Cell Survival and Axonal Regeneration in Optic Nerve Damage Models
Journal of Ocular Pharmacology and Therapeutics · 2008 · Animal Study
Telomerase Reactivation and Telomere Length Restoration by Epithalon in Cultured Human Lymphocytes
Bulletin of Experimental Biology and Medicine · 2008 · In Vitro
Epithalon Effects on Cellular Senescence and p16/INK4a Expression in Aging Fibroblasts
Bulletin of Experimental Biology and Medicine · 2007 · In Vitro
Epithalon Increases BDNF Expression and Promotes Neurogenesis in Aging Hippocampus
Neuroscience · 2007 · Animal Study