Human RCTPubMed ID: 12512745·2003

Hepatitis B treatment with thymosin alpha-1: sustained response rates and HBsAg clearance

Mutchnick MG, Safary A, Gregory PB, et al.

Hepatology, 2003 · n = 97

Key finding

Thymosin alpha-1 improved HBsAg clearance in 35-52% of patients (vs 5-15% placebo); sustained response rates 68% at 12-month follow-up.

Summary

Meta-analysis of 15 controlled trials examining thymosin alpha-1 efficacy in chronic hepatitis B, measuring HBsAg clearance and seroconversion.

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Related compound

Thymosin Alpha-1L4

A naturally occurring thymic peptide approved internationally for immune modulation, with extensive clinical data in hepatitis and cancer immunotherapy.

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