In VitroPubMed ID: 12939220·2003

Dendritic cell maturation and activation by thymosin alpha-1

Tuthill CW, Younes A, Neville DM Jr.

Journal of Immunotherapy, 2003

Key finding

Thymosin alpha-1 increased DC HLA-DR, CD80, CD86 expression; enhanced naive CD4+ T-cell proliferation 4.8-fold in co-culture.

Summary

Mechanistic study of thymosin alpha-1 effects on dendritic cell phenotype, maturation markers, and T-cell stimulatory capacity.

Read the study

The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.

View on PubMed

Related compound

Thymosin Alpha-1L4

A naturally occurring thymic peptide approved internationally for immune modulation, with extensive clinical data in hepatitis and cancer immunotherapy.

More research on Thymosin Alpha-1

COVID-19 immunotherapy: thymosin alpha-1 efficacy in severe disease

Cytokine · 2021 · Human RCT

Combination immunotherapy: thymosin alpha-1 with checkpoint inhibitors in cancer

Journal for ImmunoTherapy of Cancer · 2020 · Human Pilot

Thymalfasin: clinical pharmacology and antiviral applications

BioDrugs · 2010 · Review

Thymosin alpha-1 safety profile: adverse events across 50+ clinical trials

Current Aging Science · 2010 · Review

Thymosin alpha-1 and thymic regeneration in aging

Nature Immunology · 2009 · Animal Study