In VitroPubMed ID: 15949895·2005

TNF-α and IL-2 modulation by thymosin alpha-1 in immune cells

Blanc M, Alves-Paris MC, Collin V, et al.

Molecular Immunology, 2005

Key finding

Thymosin alpha-1 increased IL-2 and IFN-γ production (2.1-fold); modestly increased TNF-α; shifted immune response toward Th1 phenotype.

Summary

Mechanistic study of thymosin alpha-1 effects on pro-inflammatory and anti-inflammatory cytokine production in T-cells and macrophages.

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Related compound

Thymosin Alpha-1L4

A naturally occurring thymic peptide approved internationally for immune modulation, with extensive clinical data in hepatitis and cancer immunotherapy.

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