Animal StudyPubMed ID: 18200041·2008

Melanotan II and photoprotection: mechanisms of UV tolerance and melanosome function

Schweitzer AD, Hofer TP, Eckardt BA, et al.

Journal of Investigative Dermatology, 2008

Key finding

Melanotan II pretreatment reduced CPD-positive cells by 68% after UVB exposure; protection correlated with melanin density (r=0.81).

Summary

Study examining whether melanotan II-induced pigmentation provides photoprotective effects in rodent skin against UV-induced DNA damage.

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