Human PilotPubMed ID: 19740142·2009

Melanotan II in scleroderma and vitiligo: pilot studies of MC1R activation

Ortonne JP, Passeron T.

Pigment Cell & Melanoma Research, 2009 · n = 12

Key finding

Modest repigmentation observed in vitiligo patches in 3 of 8 subjects; results inconclusive due to small sample and spontaneous vitiligo variability.

Summary

Preliminary studies examining melanotan II effects in depigmented skin conditions, including vitiligo and scleroderma-associated hypopigmentation.

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Related compound

Melanotan IIL3

A melanocortin receptor agonist that stimulates melanin production (tanning) and has sexual function effects. Significant safety concerns.

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