In VitroPubMed ID: 20135106·2010

Selank Modulates GABA-Ergic Transmission and Enhances GABA-A Receptor Function

Karamyan VT, Fesenko EE, Oganyan A.

Journal of Neural Transmission, 2010

Key finding

Selank enhanced GABA-A mediated chloride currents by 67% and potentiated GABA-ergic inhibition of pyramidal neurons.

Summary

Electrophysiologic study examining selank effects on GABA-A receptor coupling, chloride current, and GABAergic neuron activity.

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Related compound

SelankL3

A synthetic peptide analog of tuftsin, approved in Russia for anxiety and studied for nootropic and immunomodulatory properties.

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