Human RCTPubMed ID: 22426806·2012

Pharmacogenetic Polymorphisms and Selank Response: Individual Differences in BDNF and Dopamine Transporter Genes

Oganyan A, Karamyan VT, Petrosyan A, et al.

Journal of Clinical Psychopharmacology, 2012 · n = 142

Key finding

BDNF Met allele carriers showed 64% response rate versus 42% Val/Val (p<0.05); DAT1 10-repeat associated with faster anxiety reduction.

Summary

Pharmacogenetic study correlating BDNF Val66Met and DAT1 polymorphisms with individual selank response in anxiety patients.

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Related compound

SelankL3

A synthetic peptide analog of tuftsin, approved in Russia for anxiety and studied for nootropic and immunomodulatory properties.

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