Human RCTPubMed ID: 36423456·2023

Tirzepatide Efficacy in Lipid Management

Fonseca VA, Desai S, Ceglia L, et al.

Circulation, 2023 · n = 465

Key finding

Tirzepatide reduced triglycerides by 37% (p<0.001), LDL by 12%, and increased HDL by 8% versus baseline; improvements beyond weight loss.

Summary

Trial demonstrating tirzepatide improved triglycerides and LDL cholesterol independent of weight loss.

Read the study

The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.

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Related compound

TirzepatideL5

An FDA-approved dual GIP/GLP-1 receptor agonist that has shown the highest weight loss results of any approved medication.

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