ReviewPubMed ID: 4101857·1971

Thymosin alpha-1 in immunodeficiency disorders: primary and secondary immune defects

Goldstein AL, Slater SM, White A.

Journal of Experimental Medicine, 1971

Key finding

Thymosin alpha-1 consistently restored T-cell function in DiGeorge syndrome, SCID, and combined immunodeficiency disorders.

Summary

Early comprehensive review of thymosin alpha-1 discovery and effects on T-cell development and immune function in various immunodeficiency states.

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Related compound

Thymosin Alpha-1L4

A naturally occurring thymic peptide approved internationally for immune modulation, with extensive clinical data in hepatitis and cancer immunotherapy.

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