Pharmacology
GH Pulsatility
The rhythmic, episodic secretion of growth hormone from the pituitary.
Definition
Growth hormone is released in pulses rather than continuously. Pulsatility is thought to be essential for healthy GH signaling; GHRH analogs and ghrelin agonists preserve it, while exogenous GH does not.
Related terms
- GHRH ReceptorPituitary receptor for growth hormone-releasing hormone; target of sermorelin, CJC-1295, and tesamorelin.
- Ghrelin Receptor (GHSR-1a)The growth hormone secretagogue receptor bound by ghrelin, ipamorelin, and MK-677.
- PituitaryEndocrine gland at the base of the brain — source of growth hormone and other hormones.
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