GHRH Receptor

Definition

GHRHR is a class B GPCR on pituitary somatotrophs. Activation stimulates synthesis and pulsatile release of growth hormone.

Related terms

• GPCRG-protein coupled receptor — a family of membrane receptors that transduce signals via heterotrimeric G proteins.
• PituitaryEndocrine gland at the base of the brain — source of growth hormone and other hormones.
• GH PulsatilityThe rhythmic, episodic secretion of growth hormone from the pituitary.

Compounds that reference GHRH Receptor

• CJC-1295A growth hormone-releasing hormone (GHRH) analog studied for its ability to increase growth hormone and IGF-1 levels.
• SermorelinA growth hormone-releasing hormone analog with a long history of clinical use for GH deficiency diagnosis and therapy.
• TesamorelinAn FDA-approved GHRH analog used for HIV-associated lipodystrophy, with research into broader metabolic and cognitive applications.