Biochemistry
Hypothalamus
Brain region controlling pituitary function, appetite, and circadian rhythm.
Definition
The hypothalamus integrates endocrine and autonomic function. GLP-1 and melanocortin peptides act on hypothalamic circuits to modulate appetite and sexual behavior.
Related terms
- PituitaryEndocrine gland at the base of the brain — source of growth hormone and other hormones.
- GLP-1 ReceptorA class B GPCR activated by glucagon-like peptide-1; target of semaglutide, tirzepatide, and related agents.
- Melanocortin 4 Receptor (MC4R)Hypothalamic receptor that mediates appetite suppression and sexual arousal; target of PT-141.
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