In VitroPubMed ID: 10326922·1999

Melanotan II potency and stability: formulation optimization for clinical use

Hadley ME, Haskell-Luevano C.

Journal of Medicinal Chemistry, 1999

Key finding

Melanotan II stability decreased 18% per week at 25°C; cyclization enhanced stability 3.5-fold; optimized formulations maintained >95% potency for 24 months.

Summary

Chemical stability and receptor binding studies of melanotan II and analogs under various conditions, informing formulation strategies.

Read the study

The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.

View on PubMed

Related compound

Melanotan IIL3

A melanocortin receptor agonist that stimulates melanin production (tanning) and has sexual function effects. Significant safety concerns.

More research on Melanotan II

Illegal melanotan II products: purity analysis and contamination screening

JAMA Internal Medicine · 2014 · Review

Spontaneous erections and libido enhancement in men using melanotan II

International Journal of Impotence Research · 2011 · Human Pilot

Nevi development and monitoring during melanotan II therapy

Melanoma Research · 2010 · Review

Melanotan II in scleroderma and vitiligo: pilot studies of MC1R activation

Pigment Cell & Melanoma Research · 2009 · Human Pilot

Melanotan II and photoprotection: mechanisms of UV tolerance and melanosome function

Journal of Investigative Dermatology · 2008 · Animal Study