Animal StudyPubMed ID: 15897340·2005

Thermal stress and melanotan II: heat dissipation and thermoregulation effects

Kellogg DL Jr, Liu Y, Kosiba IF, et al.

Journal of Applied Physiology, 2005

Key finding

Melanotan II impaired cutaneous vasodilation response to heat; reduced sweating capacity by 22%; consistent with MC1R-mediated alpha-MSH pathway.

Summary

Study of melanotan II effects on cutaneous vasodilation, sweating, and thermoregulatory responses during thermal stress.

Read the study

The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.

View on PubMed

Related compound

Melanotan IIL3

A melanocortin receptor agonist that stimulates melanin production (tanning) and has sexual function effects. Significant safety concerns.

More research on Melanotan II

Illegal melanotan II products: purity analysis and contamination screening

JAMA Internal Medicine · 2014 · Review

Spontaneous erections and libido enhancement in men using melanotan II

International Journal of Impotence Research · 2011 · Human Pilot

Nevi development and monitoring during melanotan II therapy

Melanoma Research · 2010 · Review

Melanotan II in scleroderma and vitiligo: pilot studies of MC1R activation

Pigment Cell & Melanoma Research · 2009 · Human Pilot

Melanotan II and photoprotection: mechanisms of UV tolerance and melanosome function

Journal of Investigative Dermatology · 2008 · Animal Study