Once-daily administration of CJC-1295, a long-acting GHRH analog, normalizes growth in the GHRH knockout mouse
Alba M, Fintini D, Bowers CY, et al.
American Journal of Physiology - Endocrinology and Metabolism, 2006
Key finding
CJC-1295 normalized body weight, body length, and organ weights in GHRH knockout mice, demonstrating full GHRH replacement capability.
Summary
Animal study demonstrating once-daily CJC-1295 completely normalized growth in GHRH-deficient mice, proving it can substitute for endogenous GHRH signaling.
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