BPC-157 Enhances Peripheral Nerve Regeneration After Crush Injury
Vukojevic J, Mihovil I, Jagic V, et al.
Regulatory Peptides, 2008 · n = 52
Key finding
BPC-157 increased axonal density by 71% at 14 days, improved walking pattern recovery by 58%, and enhanced myelin thickness (p<0.001).
Summary
Intragastric BPC-157 accelerated sciatic nerve regeneration following crush injury with improved functional recovery and axonal sprouting.
Read the study
The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.
View on PubMedRelated compounds
A gastric pentadecapeptide studied extensively in animal models for tissue healing, gut protection, and cytoprotective properties. Despite over 100 preclinical studies, human clinical data remains extremely limited.
A growth hormone-releasing hormone (GHRH) analog studied for its ability to increase growth hormone and IGF-1 levels.
More research on BPC-157
Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review
Sports Health · 2025 · Review
Safety of Intravenous Infusion of BPC157 in Humans: A Pilot Study
Alternative Therapies in Health and Medicine · 2025 · Human Pilot
The Stable Gastric Pentadecapeptide BPC 157 Pleiotropic Beneficial Activity and Its Possible Relations with Neurotransmitter Activity
Pharmaceuticals · 2024 · Review
Stable Gastric Pentadecapeptide BPC 157 and Wound Healing
Frontiers in Pharmacology · 2021 · Review
Modulatory effects of BPC 157 on vasomotor tone and the activation of Src-Caveolin-1-endothelial nitric oxide synthase pathway
Scientific Reports · 2020 · Animal Study