Animal StudyPubMed ID: 16857213·2006

Sustained GH Secretion with CJC-1295 DAC: Mechanism and Duration

Hansen BS, Raun K, Johansen NL, et al.

Peptides, 2006 · n = 18

Key finding

DAC modification increased CJC-1295 half-life 30-fold (from 2 to 60+ hours), with albumin binding preventing renal clearance.

Summary

Preclinical study elucidating DAC-mediated albumin binding mechanism enabling sustained GH release.

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Related compound

CJC-1295L3

A growth hormone-releasing hormone (GHRH) analog studied for its ability to increase growth hormone and IGF-1 levels.

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