Human PilotPubMed ID: 17018654·2006

Pulsatile secretion of growth hormone persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog

Ionescu M, Bhatt DL.

Journal of Clinical Endocrinology & Metabolism, 2006 · n = 21

Key finding

CJC-1295 preserves pulsatile GH secretion during continuous stimulation — the enhanced trough GH levels (not pulse amplitude) drive the IGF-1 increase.

Summary

Detailed GH pulsatility analysis showing CJC-1295 DAC increased both trough and mean GH while preserving natural pulsatile secretion pattern.

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Related compound

CJC-1295L3

A growth hormone-releasing hormone (GHRH) analog studied for its ability to increase growth hormone and IGF-1 levels.

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