Animal StudyPubMed ID: 18283677·2008

AOD 9604 and Articular Cartilage Repair: Assessment in a Rat Cartilage Defect Model

Black A, Huang AH, Yin Z, et al.

Journal of Orthopaedic Research, 2008

Key finding

AOD 9604 (0.1-10 mcg/kg) promoted cartilage repair with 52% defect filling versus 8% in controls; improved collagen organization.

Summary

Rat model of articular cartilage defect treated with local and systemic AOD 9604 measuring cartilage repair and collagen synthesis.

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Related compound

AOD-9604L2

A modified fragment of human growth hormone studied for fat metabolism without the growth-promoting effects of full GH.

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