Animal StudyPubMed ID: 19324939·2009

AOD 9604 Reduces Leptin Levels and Improves Leptin Sensitivity in High-Fat Diet Obese Rats

Liu B, Duong T, Nusser J, et al.

Diabetes, 2009

Key finding

AOD 9604 reduced serum leptin by 56%, improved hypothalamic STAT3 phosphorylation, and restored leptin-induced POMC expression.

Summary

Study in diet-induced obese rats examining AOD 9604 effects on serum leptin levels and hypothalamic leptin receptor signaling.

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The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.

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Related compound

AOD-9604L2

A modified fragment of human growth hormone studied for fat metabolism without the growth-promoting effects of full GH.

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