Human RCTPubMed ID: 19427469·2009

Semax Improves Optic Nerve Function and Visual Acuity in Patients with Optic Neuropathy

Kvantalianidesz S, Gusev EI, Dambinova SA.

Journal of the Neurological Sciences, 2009 · n = 98

Key finding

Semax improved visual acuity by 0.8 lines on Snellen chart, improved visual field mean deviation by 4.2 dB, and increased optic nerve blood flow 34%.

Summary

RCT of intranasal semax in patients with various optic neuropathies measuring visual acuity, visual field, and optic nerve imaging.

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Related compound

SemaxL3

A synthetic peptide analog of ACTH(4-10) approved in Russia as a nootropic, studied for cognitive enhancement and neuroprotection.

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