Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review
Vasireddi N, Hahamyan H, Salata MJ, et al.
Sports Health, 2025
Key finding
Despite broad preclinical support across muscle, tendon, ligament, and bone models, only one clinical study exists for musculoskeletal applications, leaving a significant gap between animal and human evidence.
Summary
Systematic review of 36 studies (1993-2024) examining BPC-157 in musculoskeletal healing. Found 35 preclinical studies and only 1 clinical study. Concluded BPC-157 promotes healing by boosting growth factors and reducing inflammation.
Read the study
The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.
View on PubMedRelated compound
More research on BPC-157
Safety of Intravenous Infusion of BPC157 in Humans: A Pilot Study
Alternative Therapies in Health and Medicine · 2025 · Human Pilot
The Stable Gastric Pentadecapeptide BPC 157 Pleiotropic Beneficial Activity and Its Possible Relations with Neurotransmitter Activity
Pharmaceuticals · 2024 · Review
Stable Gastric Pentadecapeptide BPC 157 and Wound Healing
Frontiers in Pharmacology · 2021 · Review
Modulatory effects of BPC 157 on vasomotor tone and the activation of Src-Caveolin-1-endothelial nitric oxide synthase pathway
Scientific Reports · 2020 · Animal Study
Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts
Molecules · 2014 · In Vitro