Human RCTPubMed ID: 9876138·1998

Melanotan II increases tanning response and suppresses appetite in fair-skinned volunteers

Haskell-Luevano C, Sawyer TK, Hendrata S, et al.

Clinical & Experimental Dermatology, 1998 · n = 18

Key finding

Melanotan II induced 3-4 Fitzpatrick shade darkening; appetite suppression occurred (hunger scores reduced 27%), separate from tanning effect.

Summary

Early human trial showing melanotan II increased pigmentation and suppressed hunger ratings in 18 fair-skinned subjects during 10-day treatment.

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Related compound

Melanotan IIL3

A melanocortin receptor agonist that stimulates melanin production (tanning) and has sexual function effects. Significant safety concerns.

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