Thymosin beta4 accelerates wound healing
Malinda KM, Sidhu GS, Mani H, et al.
Journal of Investigative Dermatology, 1999
Key finding
Thymosin beta-4 accelerated wound healing by 42-61% and increased wound contraction by 11% through enhanced keratinocyte migration and angiogenesis.
Summary
Foundational study showing topical or intraperitoneal Tβ4 increased re-epithelialization by 42% at day 4 and 61% at day 7 in full-thickness punch wounds.
Read the study
The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.
View on PubMedRelated compound
More research on TB-500
The regenerative peptide thymosin β4 accelerates the rate of dermal healing in preclinical animal models and in patients
Annals of the New York Academy of Sciences · 2012 · Human Pilot
TB-500 Improves Neurological Recovery After Traumatic Brain Injury
Journal of Neurotrauma · 2011 · Animal Study
Thymosin β4: a multi-functional regenerative peptide. Basic properties and clinical applications
Expert Opinion on Biological Therapy · 2010 · Review
Thymosin Beta-4 Regulates Inflammation and Promotes Macrophage M2 Polarization
Journal of Molecular Medicine · 2010 · In Vitro
Thymosin beta4 and cardiac repair
Annals of the New York Academy of Sciences · 2009 · Animal Study