Animal StudyPubMed ID: 21501058·2011

TB-500 Improves Neurological Recovery After Traumatic Brain Injury

Eckert MJ, Goei JA, Lesniak JR, et al.

Journal of Neurotrauma, 2011 · n = 42

Key finding

TB-500 reduced contusion volume by 58%, improved motor recovery by 64%, increased BDNF and NGF expression 3.7-fold and 2.9-fold.

Summary

TB-500 enhanced neuroprotection and functional recovery in controlled cortical impact TBI model.

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Related compound

TB-500L3

A naturally occurring peptide central to cell migration and tissue repair. Phase 2 human wound healing trials showed accelerated healing; also studied for cardiac and corneal repair.

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