Animal StudyPubMed ID: 20536454·2009

Thymosin beta4 and cardiac repair

Bock-Marquette I, Shrivastava S, Pipes GT, et al.

Annals of the New York Academy of Sciences, 2009

Key finding

Tβ4 activated endogenous cardiac progenitor cells, promoted coronary vessel growth, and improved cardiac function after myocardial infarction in mice.

Summary

Study showing Tβ4 is the first molecule to simultaneously trigger myocardial and vascular regeneration after systemic administration in animal MI models.

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The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.

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Related compound

TB-500L3

A naturally occurring peptide central to cell migration and tissue repair. Phase 2 human wound healing trials showed accelerated healing; also studied for cardiac and corneal repair.

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