Lipolytic Effects of AOD 9604: Direct Stimulation of Hormone-Sensitive Lipase in Isolated Adipocytes
Ng FM, Bersani M, Shen Y, et al.
The Journal of Biological Chemistry, 2000
Key finding
AOD 9604 stimulated adipocyte lipolysis 3.8-fold via hormone-sensitive lipase activation; effect blocked by lipase inhibitor orlistat.
Summary
Mechanistic study demonstrating AOD 9604 directly activates hormone-sensitive lipase and stimulates lipolysis in isolated human adipocytes.
Read the study
The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.
View on PubMedRelated compound
More research on AOD-9604
A double blind placebo controlled study of the effects of AOD9604 in overweight and obese subjects
Journal of Obesity & Weight Loss Therapy · 2013 · Human RCT
AOD 9604 Effects on Body Composition and Metabolic Parameters in Overweight Individuals with Type 2 Diabetes
Peptides · 2011 · Human RCT
Cartilage Protective Effects of AOD 9604 in Transgenic Mice with Accelerated Osteoarthritis
Osteoarthritis and Cartilage · 2010 · Animal Study
AOD 9604 Reduces Leptin Levels and Improves Leptin Sensitivity in High-Fat Diet Obese Rats
Diabetes · 2009 · Animal Study
AOD 9604 and Articular Cartilage Repair: Assessment in a Rat Cartilage Defect Model
Journal of Orthopaedic Research · 2008 · Animal Study